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Anti-ECSIT antibody (ab21288)抗ECSIT抗體

簡要描述:Anti-ECSIT antibody (ab21288)
貨號:ab21288
廠家:Abcam公司
規格:100ug
保存溫度:-20℃ 和 2~8℃
貨期:現貨2~5天,期貨2-3周

  • 產品型號:ab21288
  • 廠商性質:代理商
  • 更新時間:2017-09-29
  • 訪  問  量:1272
詳細介紹

Anti-ECSIT antibody (ab21288)抗ECSIT抗體產品信息:

  • Product nameAnti-ECSIT antibody
  • Description

    Rabbit polyclonal to ECSIT

  • Tested applicationsICC/IF, IP, IHC-P, WB
  • Species reactivity

    Reacts with: Mouse, Human

  • Immunogen

    Synthetic peptide corresponding to 14 amino acids near the C-terminus of ECSIT (Human).

  • Positive control
    • human heart lysate

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration 100 µg at 1 mg/ml

  • Purification notesIon exchange chromatography.
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas
    • Signal Transduction
    • Signaling Pathway
    • Nuclear Signaling
    • NFkB Pathway
    • Immunology
    • Innate Immunity
    • TLR Signaling

Applications

Our Abpromise guarantee covers the use of ab21288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

ApplicationNotes
ICC/IFICC/IF: Use at an assay dependent dilution. PubMed: 21163940
IPIP: Use at an assay dependent dilution. PubMed: 21163940
IHC-PIHC-P: Use a concentration of 2 µg/ml.
WBWB: Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximay 42 kDa (predicted molecular weight: 49 kDa).

Target

  • FunctionAdapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity). Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
  • Sequence similaritiesBelongs to the ECSIT family.
  • Cellular localizationCytoplasm. Nucleus. Mitochondrion.
  • Database links

    • Entrez Gene: 51295 Human
    • Entrez Gene: 26940 Mouse
    • Omim: 608388 Human
    • SwissProt: Q9BQ95 Human
    • SwissProt: Q9QZH6 Mouse
    • Unigene: 515146 Human
    • Unigene: 425568 Mouse
    • Alternative names

      • Ecsit antibody
      • ECSIT homolog antibody
      • ECSIT protein antibody

    Anti-ECSIT antibody images

    • Western blot - ECSIT antibody (ab21288)

      Western blot - ECSIT antibody (ab21288)

      Lane 1 : Anti-ECSIT antibody (ab21288) at 0.5 µg/ml
      Lane 2 : Anti-ECSIT antibody (ab21288) at 1 µg/ml
      Lane 3 : Anti-ECSIT antibody (ab21288) at 2 µg/ml

      Lane 1 : human heart lysate
      Lane 2 : human heart lysate
      Lane 3 : human heart lysate


      Predicted band size : 49 kDa
      Observed band size : 42 kDa (why is the actual band size different from the predicted?)

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ECSIT antibody (ab21288)

      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ECSIT antibody (ab21288)

      ab21288 at 2µg/ml staining ECSIT in mouse heart by IHC

    公司介紹:

        Abcam位于英國的劍橋科學園,成立于1998年,專門生產和分銷研究型抗體。主要創立人Jonathan Milner和實驗室同事構思成立一間了解科研人員需要的網上抗體公司,理念是Abcam銷售質量高的抗體,并提供zui全面、誠實、時新的說明書,快速的送貨服務,及高效率的顧客和服務。我們的在線目錄(ladywindows.cn) 已有差不多100,000種抗體和試劑,并不斷添加,供應予百多個國家。Abcam200511月在倫敦證券交易所上市,在美國馬薩諸塞州、日本東京及香港均設有分公司。

        Abcam 一直致力加強產品線,為使研究員更容易找到蛋白質研究試劑產品,在2011并購了美國的MitoSciences公司,加強了免疫分析方面的產品供應;同年也并購了英國的Ascent Scientific 公司,開展了生化試劑的供應。在2012年,Abcam并購了美國的Epitomics 公司,成為一家有的RabMAbs® 供應商。

        Abcam 的 目標是給世界上的抗體建立zui大的在線目錄,為各地科學家提供*產品,成為各國科學界的重要伙伴。我們為所有產品提供來使客戶獲得預期的結 果。為提供高質量的抗體來指向盡可能多的靶蛋白,我們盡所能在盡可能多的應用和物種中檢測每種抗體。我們相信誠信才是上策,在我們的上會發布有關我們 每一種產品的盡可能多的信息。

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